Bernard et al. Hypothermia after cardiac arrest RCT. NEJM 2002

Paper type

Multi-centre Randomised Controlled Trial

Reference

SA Bernard Sa et al.
Treatment of Comatose Survivors of out-of-hospital Cardiac Arrest with Induce Hypothermia
NEJM 2002 346:8;557-63

Therapeutic hypothermia following an Out-of-Hospital Cardiac arrest reduces morbidity. NNT 4 for one additional good neurological outcome.

• PubMed Abstract  
• Scottish Intensive Care Society CAT review of paper

Point for discussion:

Exactly when should the therapeutic hypothermia be started and how best to do it?